Executive Summary of Initiative 2.3

 

Chronic and acute pain affects ~100 million people in America and greatly increases national rates of morbidity, mortality, and disability. Pain not only imposes enormous national economic costs; it negatively impacts people’s lives in significant ways. The misuse of and addiction to opioids (i.e., prescription pain relievers, heroin, and synthetic opioids such as fentanyl) is a serious national crisis that affects public health as well as social and economic welfare (i.e., 130 people die of opioid overdose every day in the US).  In 2018, the opioid-overdose death rate rose to over 40,000/year US.

This Center is designed around the Health Sciences Strategic Plan, pillar 2 "Health, Wellbeing, and Quality Care for All”  This Center address the opioid-epidemic, future addiction crisis, the aging population that is stricken with chronic pain and the need to develop and enrich our chronic pain and addiction clinical research.  The Center will help expand a successful preclinical pain and addiction research entity by adding professionals in addiction medicine, clinical research and clinical trials. This Center, in partnership with the college of pharmacy and chemistry/biochemistry, will create a new drug discovery program.  In collaboration with the college of public health, this center will take on a large education and legislation mission on substance abuse across the state.  Finally, this new center will partner with the college of engineering to develop novel technology in helping predict and prevent patients with substance abuse liability. The creation of this center will facilitate closer and more effective communications and promote collaboration between clinician and researchers to identify clinical deficiencies and solutions. 

 

2.3A Lead in Alternative Pain Management Drug Discovery

Design novel compounds for specific molecular entities with potential to significantly attenuate chronic pain that do not result in    rewarding behaviors or lead to substance misuse. Such compounds will have appropriate pharmacokinetics for clinical trials. Make sure such compounds are safe and put forth towards an IND approval for clinical trials.

 

 

2.3B Explore new Treatment and Rehabilitation Approaches 

Develop innovative therapies and approaches for patients with chronic pain to inhibit or significantly reduce the use of addictive substances, like opioids.  Create strategies to address the mental illness of substance abuse.

 

 

2.3C Work with Prescribing Providers of Controlled Substances to Prevent Substance use Disorder and Reduce the Morbidity and Mortality

Develop innovative therapies and approaches for patients with chronic pain to inhibit or significantly reduce the use of addictive substances, like opioids.  Create strategies to address the mental illness of substance abuse.

 

 

2.3D Build Preventative Approaches and Tools to Screen At-Risk Individuals

Align UAHS policies, teaching content, and practices to go beyond the academic role of identifying the problem, diagnosing and         reciting standard rules. Tackle prevention by educating patients with direct to consumer marketing, screening for high risk behaviors and proficiently diagnosing with new tools.

 

 

Board of Directors


Renee Gregg FNP,DNP

CON-T, Interim Coordinator, FNP Specialty, Clinical Associate Professor, Nursing

Maria Manriquez

Director, Pain and Addiction Curriculum, Professor, Obstetrics and Gynecology

 

Daniel Derksen

CoPH-T Director for Center of Rural Health, Professor, Public Health - Professor, Family and Community Medicine  Associate Vice President, Health/Equity-Outreach and Interprofessional Activities Senior Advisor, Arizona Area Health Education Center Program

Jerry McCoy

Interim Department Chair, Anesthesiology Clinical Associate Professor, Anesthesiology

 

Rick Shnellmann

Dean, Pharmacy - Professor, Pharmacology and Toxicology Professor, Medicine -Professor, Physiological Sciences - GIDP, Endowed Chair, Howard J Schaeffer - Pharmaceutical Sciences - Professor, BIO5 Institute